Sasaki S, Stevens J K, Bodick N
Brain Res. 1983 Jan 24;259(2):193-206. doi: 10.1016/0006-8993(83)91250-7.
Serial reconstruction at the EM level of cat retinal ganglion cell dendrites reveals that: (1) the microtubular array is discontinuous, (2) microtubular endings are associated with smooth endoplasmic reticulum (SER), mitochondria, and plasma membrane, (3) individual microtubules always maintain a minimum distance from other microtubules (87 nm), SER (43 nm) and plasma membrane (69 nm), and (5) individual microtubules can 'wander' independent of adjacent microtubules throughout the dendritic volume. These observations, taken with some recent biochemical and immunohistochemical data by other workers, suggest that the microtubules are surrounded by a coat of high molecular weight, microtubular-associated proteins (HMW MAPs), which effectively creates a 90 nm tube around a central microtubular core. Our results suggest that bundles of these 'MAP-tubes' may serve as a major component of the dendritic cytoskeleton in the cat ganglion cells.
（1）微管阵列是不连续的；（2）微管末端与滑面内质网（SER）、线粒体和质膜相关联；（3）单个微管与其他微管（87纳米）、SER（43纳米）和质膜（69纳米）始终保持最小距离；（4）单个微管可在整个树突体积内独立于相邻微管“游走”。这些观察结果与其他研究人员最近的一些生化和免疫组织化学数据相结合，表明微管被一层高分子量的微管相关蛋白（HMW MAPs）所包围，这实际上在中央微管核心周围形成了一个90纳米的管道。我们的结果表明，这些“MAP管”束可能是猫神经节细胞树突细胞骨架的主要组成部分。
