Ottenjann R, Kunert H, Kühner W, Seib H J
Dtsch Med Wochenschr. 1983 Feb 18;108(7):246-9. doi: 10.1055/s-2008-1069535.
Islands of gastric mucosa were sought in non-selected in- and out-patients undergoing endoscopy. Mucosal islands were found in 40 patients (out of approximately 1000 oesopho-gastroduodenoscopies), mostly a few centimetres below the mouth of the oesophagus. Histology showed "pure" corpus mucosa in 24 cases, a combination of fundus glands (with zymogenic and parietal cells) and mucoid glands were shown in 9 cases; the rest had only mucoid glands (3 cases) or surface elements of gastric mucosa (two cases). In two cases the islands were missed in the biopsy. In one case the demonstration of HCl secretion from a corpus mucosal island could be achieved by local application of congo red via endoscope after stimulation with pentagastrin. The pathogenetic significance of HCl-producing gastric mucosal islands in the cervical oesophagus is due to their ability to induce peptic lesions with subsequent web or membrane formation.
在接受内镜检查的非选择性门诊和住院患者中寻找胃黏膜岛。在大约1000例食管胃十二指肠镜检查中，有40例发现了黏膜岛，大多位于食管口下方几厘米处。组织学检查显示，24例为“纯”胃体黏膜，9例为胃底腺（含主细胞和壁细胞）与黏液腺的组合；其余患者仅有黏液腺（3例）或胃黏膜表面成分（2例）。有2例在活检时未发现这些岛状组织。在1例中，通过在内镜下经五肽胃泌素刺激后局部应用刚果红，可证实胃体黏膜岛分泌盐酸。颈段食管中产生盐酸的胃黏膜岛的致病意义在于其诱导消化性病变并随后形成蹼或膜的能力。
