Suppr超能文献

[咪唑并(1,2-f)黄嘌呤衍生物对大脑皮层生物电活动及诱发电位的影响]

[Effect of imidazo(1,2-f)xanthine derivatives on cerebral cortical bioelectrical activity and evoked potentials].

作者信息

Samura B A

出版信息

Farmakol Toksikol. 1983 Jan-Feb;46(1):17-20.

PMID:6825813
Abstract

Potassium salt of 8-bromotheophylline was made interact with alpha-bromoketones to obtain initial products (7-acylalkyl-8-bromotheophyllines) for the synthesis of the derivatives of 1H-imidazo(1,2-f)xanthine. 1-(beta-Oxyethyl)-2,3,6,8-tetramethylimidazo(1,2-f)xanthine and 1,2,6,8-tetramethylimidazo (1,2-f)xanthine were discovered to have a stimulant effect on the central nervous system, to increase the amplitude of evoked potentials of the visceral, auditory and cutaneous projection zones of the brain cortex, and to improve rhythm assimilation.

摘要

使8-溴茶碱钾盐与α-溴代酮相互作用,以获得用于合成1H-咪唑并(1,2-f)黄嘌呤衍生物的初始产物(7-酰基烷基-8-溴茶碱)。发现1-(β-氧乙基)-2,3,6,8-四甲基咪唑并(1,2-f)黄嘌呤和1,2,6,8-四甲基咪唑并(1,2-f)黄嘌呤对中枢神经系统有兴奋作用,可增加大脑皮层内脏、听觉和皮肤投射区诱发电位的幅度,并改善节律同化。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验