Fibronectin in foreign body-induced sarcomas and preneoplastic cells.
作者信息
MacDonald G C, Furcht L T, Brand K G
出版信息
Proc Soc Exp Biol Med. 1983 Jan;172(1):89-92. doi: 10.3181/00379727-172-41532.
PMID:6828457
Abstract
Foreign body (FB)-induced murine sarcoma cells and advanced preneoplastic cells as well as normal fibroblasts produce fibronectin (FN) in primary culture; cells at early preneoplasia do not. Hence, the neoplastic properties of FB-induced sarcomas do not depend on absence of FN. Temporary FN repression during early preneoplasia is associated with certain phenotypic cell characteristics.
摘要
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