Clark N, Corbin S
Public Health Rep. 1983 Jan-Feb;98(1):53-6.
In three quarters of a century of observation and research, the effects of fluoride on dental caries and on general bodily health have been well documented. An expanding data base has allowed a firming up of the guidance and standards for appropriate and safe levels of naturally occurring fluorides for human consumption. Over time, through specific recommendations, the maximum fluoride concentrations deemed appropriate have been altered, but by a process of considered adjustment. Although the Public Health Service has been responsible for the formalization of many of the recommended standards, those recommendations have been based on research from many fronts. In the most recent reconsideration of the standards for natural fluoride, the most exhaustive and thoroughly documented review to date was done, incorporating review by representatives from State, Federal, and private programs. Although the specific example of the development of standards for natural fluoride is used, it should be illustrative of similar processes that are constantly underway in regard to substances and factors with a potential impact on the public's health. Expansion of the data base through research and scientific inquiry will lay the foundation for future reconsideration of the standards for naturally occurring fluorides.
在长达四分之三个世纪的观察与研究中,氟化物对龋齿及人体总体健康的影响已有充分记录。不断扩充的数据库使得关于人类摄入天然氟化物的适宜与安全水平的指导方针和标准得以稳固。随着时间推移,通过具体建议,被视为适宜的最大氟化物浓度有所改变,但这是经过审慎调整的过程。尽管公共卫生服务部门负责将许多推荐标准正式化,但这些建议是基于多方面的研究。在最近对天然氟化物标准的重新审议中,进行了迄今为止最为详尽且记录完备的审查,纳入了州、联邦和私人项目代表的审查。尽管以天然氟化物标准制定的具体例子为例,但它应能说明针对可能影响公众健康的物质和因素正在持续进行的类似过程。通过研究和科学探究扩充数据库,将为未来重新审议天然氟化物标准奠定基础。