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慢性摄入氯化甲基汞的幼年猴子断奶后血液、毛发、粪便及尿液中汞含量的变化。

The effect of weaning on blood, hair, fecal and urinary mercury after chronic ingestion of methylmercuric chloride by infant monkeys.

作者信息

Lok E

出版信息

Toxicol Lett. 1983 Feb;15(2-3):147-52. doi: 10.1016/0378-4274(83)90208-4.

Abstract

Several studies suggest that infant animals may be more sensitive to toxic insult from methylmercury than adults. In our experiment, newly born infant monkeys were given equivalent daily doses of 50 micrograms Hg/kg body weight orally in the form of methylmercury for more than 60 weeks. Data revealed that after weaning at 200 days, both blood and hair mercury showed a sudden drop which was accompanied by an increase in fecal mercury excretion.

摘要

多项研究表明,幼龄动物可能比成年动物对甲基汞的毒性侵害更为敏感。在我们的实验中,新生幼猴以甲基汞的形式按每日每千克体重50微克汞的等效剂量口服,持续60周以上。数据显示,在200日龄断奶后,血液和毛发中的汞含量均突然下降,同时粪便中汞的排泄量增加。

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