Emirbekov E Z, Zufarova R A
Ukr Biokhim Zh (1978). 1983 Jan-Feb;55(1):72-4.
It is found that changes induced by moderate hypothermia (30 degrees C) in the brain tissue glutaminase activity and its temperature dependence are not removed after self-heating up to the body temperature of 37 degrees C. Self-heating after deep hypothermia (20 degrees C) causes a considerable increase in the brain tissues glutaminase activity at all studied incubation temperatures (37, 30, 20 and 10 degrees C) as compared to control rats and rats under hypothermia. The increase in the brain tissue glutaminase activity during self-heating of cooled animals may be considered as a compensatory reaction under conditions of a higher utilization of glutamate by the brain.
研究发现，适度低温（30摄氏度）引起的脑组织谷氨酰胺酶活性变化及其温度依赖性，在自行升温至37摄氏度的体温后并未消除。深度低温（20摄氏度）后的自行升温导致，在所有研究的孵育温度（37、30、20和10摄氏度）下，与对照大鼠和低温下的大鼠相比，脑组织谷氨酰胺酶活性显著增加。在冷却动物自行升温过程中脑组织谷氨酰胺酶活性的增加，可被视为在大脑对谷氨酸利用率较高的情况下的一种代偿反应。
