Voorhees W D, Niebauer M J, Babbs C F
Ann Emerg Med. 1983 Mar;12(3):128-35. doi: 10.1016/s0196-0644(83)80550-2.
The ability of a new modification of cardiopulmonary resuscitation (CPR) to deliver oxygen to tissues was evaluated. The method utilizes standard CPR techniques with the addition of manual abdominal compressions (congruent to 100 mm Hg) interposed between chest compressions, and is termed interposed abdominal compression-CPR (IAC-CPR). Oxygen delivery was measured by a spirometer in a closed circuit designed to permit positive-pressure ventilation synchronized with mechanical chest compression. Ventricular fibrillation was induced electrically in 10 anesthetized dogs. In each dog, trials of IAC-CPR and standard CPR were alternated every five minutes during a 30-minute period. Arterial and central venous blood pressures, oxygen consumption, and Fick cardiac output were monitored. The addition of interposed abdominal compression significantly (P less than .01) increased each of these hemodynamic indicators. Oxygen delivery increased from 4.12 +/- 0.39 ml O2/kg/min during standard CPR to 6.37 +/- 0.35 ml O2/kg/min during IAC-CPR. Arterial systolic blood pressure increased from 67 +/- 5 mm Hg to 90 +/- 5 mm Hg, while diastolic arterial blood pressure rose from 15 +/- 2 mm Hg to 33 +/- 3 mm Hg. Cardiac output increased from 19.9 +/- 2.6 ml/min/kg to 37.5 +/- 2.7 ml/min/kg.
对一种新的心肺复苏术(CPR)向组织输送氧气的能力进行了评估。该方法采用标准的心肺复苏技术,并在胸部按压之间加入手动腹部按压(相当于100毫米汞柱),被称为插入式腹部按压心肺复苏术(IAC-CPR)。在一个设计用于允许正压通气与机械胸部按压同步的闭合回路中,用肺活量计测量氧气输送量。对10只麻醉犬进行电诱导室颤。在每只犬中,在30分钟内每隔5分钟交替进行IAC-CPR和标准CPR试验。监测动脉和中心静脉血压、氧气消耗和菲克心输出量。插入式腹部按压的加入显著(P<0.01)提高了这些血流动力学指标中的每一项。氧气输送量从标准CPR期间的4.12±0.39毫升O2/千克/分钟增加到IAC-CPR期间的6.37±0.35毫升O2/千克/分钟。动脉收缩压从67±5毫米汞柱升至90±5毫米汞柱,而动脉舒张压从15±2毫米汞柱升至33±3毫米汞柱。心输出量从19.9±2.6毫升/分钟/千克增加到37.5±2.7毫升/分钟/千克。