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维生素B6依赖型癫痫:罕见病例报告

Pyridoxine-dependency seizure: report of a rare presentation.

作者信息

Krishnamoorthy K S

出版信息

Ann Neurol. 1983 Jan;13(1):103-4. doi: 10.1002/ana.410130123.

DOI:10.1002/ana.410130123
PMID:6830153
Abstract

A child developed minor motor seizures at the age of 14 months accompanied by an abnormal electroencephalogram showing single spikes and polyspikes over the vertex and frontocentral regions. Seizures continued until the age of 22 months despite administration of several standard anticonvulsants. At age 22 months, pyridoxine, 75 mg daily, was initiated and anticonvulsants were discontinued. Both the seizures and the electroencephalographic abnormality have disappeared over the ensuing 20 months with pyridoxine therapy.

摘要

一名14个月大的儿童出现轻微运动性癫痫发作,同时脑电图异常,显示头顶和额中央区域有单个尖波和多棘波。尽管使用了几种标准抗惊厥药物,但癫痫发作一直持续到22个月大。在22个月大时,开始每日服用75毫克吡哆醇,并停用抗惊厥药物。在随后的20个月吡哆醇治疗期间,癫痫发作和脑电图异常均消失。

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Pyridoxine-dependency seizure: report of a rare presentation.维生素B6依赖型癫痫:罕见病例报告
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引用本文的文献

1
Pyridoxine dependent epilepsy: a suggestive electroclinical pattern.维生素B6依赖型癫痫:一种提示性的电临床模式。
Arch Dis Child Fetal Neonatal Ed. 1999 Sep;81(2):F125-9. doi: 10.1136/fn.81.2.f125.
2
Pyridoxine responsive epilepsy: expanded pyridoxine dependency?吡哆醇反应性癫痫:吡哆醇依赖性扩大?
Arch Dis Child. 1983 Dec;58(12):1034. doi: 10.1136/adc.58.12.1034.
3
Pyridoxine-dependent seizures, clinical and therapeutic aspects.维生素B6依赖型癫痫:临床与治疗方面
Eur J Pediatr. 1991 May;150(7):452-5. doi: 10.1007/BF01958419.