Strodel W E, Talpos G, Eckhauser F, Thompson N
Arch Surg. 1983 Apr;118(4):391-7. doi: 10.1001/archsurg.1983.01390040003001.
Eighty-two symptomatic patients with carcinoid tumors of the small intestine were examined and treated over a 20-year period. Common clinical features included weight loss, diarrhea, and symptoms of intermittent bowel obstruction; 25 patients (30%) exhibited the carcinoid syndrome. Multiple carcinoid tumors occurred in 23 patients (28%), and hepatic metastases were present in 30 (37%). All patients underwent operation. The overall mortality was 7%, and the cumulative five-year survival rate was 59%. Two factors influenced prognosis after operation: hepatic metastases and incomplete resection. Other variables, including the sex and age of the patient and the size of the primary tumor, were of no additional prognostic value. Wide resection of the tumor, including regional lymph nodes, is indicated, regardless of the size of the primary tumor.
在20年期间，对82例有症状的小肠类癌患者进行了检查和治疗。常见的临床特征包括体重减轻、腹泻和间歇性肠梗阻症状；25例患者（30%）出现类癌综合征。23例患者（28%）发生多发性类癌肿瘤，30例（37%）有肝转移。所有患者均接受了手术。总死亡率为7%，累积五年生存率为59%。术后有两个因素影响预后：肝转移和切除不完全。其他变量，包括患者的性别、年龄和原发肿瘤大小，无额外的预后价值。无论原发肿瘤大小，均建议广泛切除肿瘤，包括区域淋巴结。
