全氟正丁烷。一种用于视网膜填塞的最长持续时间的气体。

Perfluoro-n-butane. A gas for a maximum duration retinal tamponade.

作者信息

Lincoff A, Lincoff H, Iwamoto T, Jacobiec F, Kreissig I

出版信息

Arch Ophthalmol. 1983 Mar;101(3):460-2. doi: 10.1001/archopht.1983.01040010460026.

DOI:10.1001/archopht.1983.01040010460026

Abstract

The behavior of the gas perfluoro-n-butane (C4F10) in the rabbit vitreous suggests that the gas might be useful as a long-term intravitreal tamponade in retinal detachment surgery. Perfluoro-n-butane was found to expand more and remain in the eye longer than any gas previously reported. A 0.3-mL bubble expanded five times and displaced the entire rabbit vitreous in three days. The volume of the bubble began to shrink after one week, but still filled more than half the eye at three weeks. The time for total disappearance was more than three months.

摘要

全氟正丁烷（C4F10）气体在兔玻璃体中的行为表明，该气体可能作为视网膜脱离手术中长期玻璃体腔内填塞物有用。发现全氟正丁烷比先前报道的任何气体膨胀更多且在眼内留存时间更长。一个0.3毫升的气泡在三天内膨胀了五倍并取代了整个兔玻璃体。气泡体积在一周后开始缩小，但在三周时仍占据眼内一半以上空间。完全消失的时间超过三个月。