Viano D C, Lau V K
Aviat Space Environ Med. 1983 Jan;54(1):16-21.
Impact velocity and chest compression are important factors in traumatic injury; however, there is no functional relationship to assess impact severity. A blunt thoracic impact of constant velocity (5-22 m/s) and prescribed contact displacement (3-46 mm) was delivered to 123 anesthetized rabbits. Myocardial and major vascular injury increased from contusion to rupture with cardiac tamponade and sudden death as either impact velocity or chest compression was independently increased. A theoretical relationship was found for impact severity: IS=VC/1-C, where V and C are impact velocity and normalized chest compression. Based on the frequency of critical/fatal injury, probit analysis gave IS=6.4 m/s as an estimate of the ED50 response in the experimental model.
撞击速度和胸部按压是创伤性损伤的重要因素;然而,目前尚无评估撞击严重程度的功能关系。对123只麻醉兔施加了恒定速度(5-22米/秒)和规定接触位移(3-46毫米)的钝性胸部撞击。随着撞击速度或胸部按压独立增加,心肌和主要血管损伤从挫伤增加到破裂,并伴有心脏压塞和猝死。发现了撞击严重程度的理论关系:IS = VC / 1 - C,其中V和C分别为撞击速度和标准化胸部按压。基于临界/致命损伤的频率,概率分析得出IS = 6.4米/秒,作为实验模型中ED50反应的估计值。