雌激素和雄激素对未成熟大鼠子宫胸苷激酶活性诱导的协同作用。
Synergistic effect of estrogen and androgen on induction of uterine thymidine kinase activities in immature rats.
作者信息
Yamada N, Sakamoto S, Okamoto R
出版信息
Biochim Biophys Acta. 1983 Jan 25;755(2):307-9. doi: 10.1016/0304-4165(83)90219-2.
PMID:6830848
Abstract
Estradiol-17 beta induced a significant increase in the uterine thymidine kinase activity with a characteristic isozyme pattern 30 h after injection into immature rats. Testosterone propionate also revealed a similar increase. Following combined injection of estradiol-17 beta and testosterone propionate, the overall and separate isozyme activities of thymidine kinase increased to nearly the total amount of those when each hormone was injected separately.
摘要
向未成熟大鼠注射17β-雌二醇后30小时，其诱导子宫胸苷激酶活性显著增加，并伴有特征性同工酶模式。丙酸睾酮也显示出类似的增加。联合注射17β-雌二醇和丙酸睾酮后，胸苷激酶的总体和各同工酶活性增加至每种激素单独注射时的总量。
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