[在生理离子强度介质中存在额外总组蛋白时的染色质重组]

[Chromatin reorganization in a medium of physiological ionic strength in the presence of additional total histone].

作者信息

Paponov V D, Skalka M, Matyashova I, Cejkova M, Strass M

出版信息

Biull Eksp Biol Med. 1983 Mar;95(3):39-42.

Abstract

The authors studied the capability of chromatin for structural reorganization in a medium of ionic strength, close to physiological one, under the effect of polyions of polycationic nature--summary histone of chromatin. Electrophoretic analysis demonstrated that like polyanions, summary histone forces out histone HI and partially histones H2B and H2A from chromatin. However, in contrast to polyanions, summary histone makes chromatin resistant to DNase-II, apparently potentiating the aggregation capability of chromatin despite the removal of histone HI.

摘要

作者研究了在接近生理离子强度的介质中，在聚阳离子性质的聚离子——染色质总组蛋白的作用下，染色质进行结构重组的能力。电泳分析表明，与聚阴离子一样，染色质总组蛋白会将组蛋白H1以及部分组蛋白H2B和H2A从染色质中排挤出来。然而，与聚阴离子不同的是，染色质总组蛋白使染色质对DNase-II具有抗性，尽管去除了组蛋白H1，但显然增强了染色质的聚集能力。

相似文献

1

[Chromatin reorganization in a medium of physiological ionic strength in the presence of additional total histone].

Biull Eksp Biol Med. 1983 Mar;95(3):39-42.

2

[Selective loss of histone H1 as a new chromatin reaction to the addition of total histone in a medium of physiological ionic strength].

Biull Eksp Biol Med. 1982 Nov;94(11):31-3.

3

[Dissociation and decompactization of chromatin by heparin in a medium of "physiologic" ionic strength].

Biull Eksp Biol Med. 1980 Sep;90(9):325-8.

4

[Structure of chromosomal deoxyribonucleoproteins. IX. Heterogeneity of chromatin subunits in vitro and location of histone H1].

Mol Biol (Mosk). 1977 Mar-Apr;11(2):294-302.

5

[Effect of the supranucleosomal chromatin organization on histone-DNA interrelations].

Biull Eksp Biol Med. 1985 May;99(5):590-2.

6

[Competitive binding of histones to DNA and the problem of chromatin self-assembly].

Biokhimiia. 1980 Sep;45(9):1539-48.

7

Semihistone protein A24 replaces H2A as an integral component of the nucleosome histone core.

Proc Natl Acad Sci U S A. 1979 Mar;76(3):1030-4. doi: 10.1073/pnas.76.3.1030.

8

[Heterogeneity of cationic proteins of chromatin from various tissues].

Biokhimiia. 1980 Sep;45(9):1630-8.

9

[Structure of chromosomal deoxyribonucleoproteins. X. Investigation of protein organization in chromosomal subunits with the aid of bifunctional agents].

Mol Biol (Mosk). 1981 Jul-Aug;15(4):824-34.

10

[Accessibility of histone oligomers to the action of trypsin in a solution or in chromatin with different degrees of compactness].

Biokhimiia. 1985 Apr;50(4):620-7.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。