Ohlmeier H, Mannebach H, Gleichmann U
Clin Cardiol. 1983 Jan;6(1):29-36. doi: 10.1002/clc.4960060104.
In 52 patients with exercise angiography (12 normals, 31 with coronary heart disease, 9 with congestive cardiomyopathy) exercise ECGs were examined for R-wave changes. An increasing R-wave amplitude was found an insensitive sign of ischemia in patients with coronary heart disease (sensitivity 29%, specificity 81%). Sensitivity and specificity of the observed ST depression in this study were 83% and 71%, respectively, as reported by others. There was no positive correlation between the changes in the R-wave amplitude and left ventricular end-diastolic volume during exercise, thus there was no proof of the existence of the so-called Brody effect in humans.
在52例行运动血管造影的患者中（12例正常者，31例冠心病患者，9例充血性心肌病患者），对运动心电图进行了R波变化检查。发现R波振幅增加是冠心病患者缺血的不敏感征象（敏感性29%，特异性81%）。如其他人所报道，本研究中观察到的ST段压低的敏感性和特异性分别为83%和71%。运动期间R波振幅变化与左心室舒张末期容积之间无正相关，因此没有证据表明人类存在所谓的布罗迪效应。
