用99mTc-吡咯烷基甲基四环素检测自发性高血压大鼠急性心肌梗死
Detection of acute myocardial infarction in spontaneously hypertensive rats by 99mTc-pyrrolidino methyl tetracycline.
作者信息
Zmbova B, Stojanova D, Stakic D, Tadzer I, Bogdanova V
出版信息
Eur J Nucl Med. 1983;8(1):10-1. doi: 10.1007/BF00263506.
PMID:6832181
Abstract
The myocardial infarct induced by isoproterenol in spontaneously hypertensive rats accumulates higher activities of 99mTc-PM tetracycline compared with the cardiac infarct in normotensive rats caused by the same method. The isoproterenol model of the myocardial necrosis was induced in intact rats without opening the thorax and is a convenient method for experimental radioisotope studies.
摘要
与采用相同方法诱导的正常血压大鼠心肌梗死相比，异丙肾上腺素诱导的自发性高血压大鼠心肌梗死积累了更高活性的99mTc-PM四环素。在完整大鼠中诱导心肌坏死的异丙肾上腺素模型无需打开胸腔，是一种用于实验放射性同位素研究的便捷方法。
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