Seshadri R, Banerji A P, Shah P N
Experientia. 1983 Feb 15;39(2):203-4. doi: 10.1007/BF01958901.
PA and PgR appear to be reliable markers of estradiol action in normal female rat mammary glands, as seen by simultaneous expression of both proteins between the ages of 61 and 131 days. However, expression of PA at certain periods, when PgR was undetectable suggests, that the extent of availability of both estradiol and progesterone at target sites may act as controlling factors in synthesis of one protein over another.
在61至131日龄的正常雌性大鼠乳腺中,PA和PgR似乎是雌二醇作用的可靠标志物,这可通过两种蛋白的同时表达看出。然而,在某些时期,当检测不到PgR时PA的表达表明,靶位点雌二醇和孕酮的可利用程度可能是控制一种蛋白相对于另一种蛋白合成的因素。