脂质体磷脂成分的结构修饰显著增强了其在循环中的稳定性。
Stability of liposomes in circulation is markedly enhanced by structural modification of their phospholipid component.
作者信息
Bali A, Dhawan S, Gupta C M
出版信息
FEBS Lett. 1983 Apr 18;154(2):373-7. doi: 10.1016/0014-5793(83)80185-9.
PMID:6832376
Abstract
Replacement of the C-2 ester group in phosphatidylcholine by the carbamyloxy function rendered its liposomes completely stable and longer living in the circulation of rats.
摘要
用氨甲酰氧基取代磷脂酰胆碱中的C-2酯基，使其脂质体在大鼠循环中完全稳定且存活时间更长。
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