Tomasini C, Castiglioni G
J Int Med Res. 1983;11 Suppl 1:38-42.
Plasma cortisol levels were determined by a radioimmunological assay in three groups of ten psoriasis patients treated with 0.05% halometasone ointment, 0.05% halometasone cream and 0.025% fluocinolone acetonide ointment, without occlusive dressings, for 7 days. Fourteen grams of the corticoid topical was applied daily (7 g/b.i.d.) to the psoriasis plaques covering an average of 25% of the body surface. No significant differences with respect to plasma cortisol values at 8 a.m. before, during and after treatment were evident in any of the three treatment groups, nor did the treatment groups significantly differ from one another with regard to their effect on the plasma cortisol levels. No side-effects were observed.
采用放射免疫分析法测定了三组银屑病患者的血浆皮质醇水平。这三组患者每组10人，分别使用0.05%卤米松软膏、0.05%卤米松乳膏和0.025%醋酸氟轻松软膏进行治疗，不采用封包敷料，疗程为7天。每天将14克皮质类固醇外用制剂（7克，每日两次）涂抹于银屑病斑块上，这些斑块平均覆盖体表的25%。三个治疗组中，任何一组在治疗前、治疗期间和治疗后的上午8点的血浆皮质醇值均无明显差异，而且各治疗组对血浆皮质醇水平的影响也无显著差异。未观察到副作用。
