关于托马霉素的研究。II. 抗肿瘤抗生素E-和Z-托马霉素的全合成。
Studies on tomaymycin. II. Total syntheses of the antitumor antibiotics, E-and Z-tomaymycins.
作者信息
Tozuka Z, Takasugi H, Takaya T
出版信息
J Antibiot (Tokyo). 1983 Mar;36(3):276-82. doi: 10.7164/antibiotics.36.276.
PMID:6833147
Abstract
The total syntheses of naturally occurring E-tomaymycin (1E) and its olefinic geometrical isomer, Z-tomaymycin (1Z) are described. The Z-isomer was found to have the same anti-bacterial activity as E-isomer (1E).
摘要
描述了天然存在的E-番茄霉素（1E）及其烯烃几何异构体Z-番茄霉素（1Z）的全合成。发现Z-异构体具有与E-异构体（1E）相同的抗菌活性。
Zotero 插件