在可透水汽的膜下进行湿性伤口愈合。

Moist wound healing under a vapor permeable membrane.

作者信息

Alper J C, Welch E A, Ginsberg M, Bogaars H, Maguire P

出版信息

J Am Acad Dermatol. 1983 Mar;8(3):347-53. doi: 10.1016/s0190-9622(83)70038-1.

Abstract

Ten ambulatory patients with unilateral and eight with bilateral ulcers of various etiologies were studied to determine the effects of keeping a wound bed moist under a water vapor and oxygen permeable membrane (VPM). In the bilateral group, VPM healing was compared with a debriding enzyme ointment and 10% benzoyl peroxide in the same patient. The faster healing rate with VPM was compared to the healing rate with control substances by the paired t test, with significance at less than 0.05 level. In the unilateral group two patients with ulcers to bone or joint capsule and one patient who had failed grafting healed without surgery. Two patients failed to heal with the VPM. All healing occurred in the face of gross bacterial contamination. Three patients treated with VPM developed cellulitis. Wound healing under a vapor permeable membrane occurs with an increase of the average healing rate by a factor of 2.6 when compared to control substances in ambulatory patients.

摘要

对10名单侧溃疡和8名双侧溃疡的门诊患者进行了研究，这些溃疡病因各异，目的是确定在水蒸气和氧气可渗透膜（VPM）下保持伤口床湿润的效果。在双侧溃疡组中，将同一患者使用VPM愈合的情况与清创酶软膏和10%过氧化苯甲酰进行了比较。通过配对t检验将VPM更快的愈合率与对照物质的愈合率进行比较，显著性水平小于0.05。在单侧溃疡组中，两名有骨或关节囊溃疡的患者和一名移植失败的患者未经手术就愈合了。两名患者使用VPM未能愈合。所有愈合均发生在存在大量细菌污染的情况下。三名接受VPM治疗的患者发生了蜂窝织炎。与门诊患者使用对照物质相比，在可渗透膜下伤口愈合时平均愈合率提高了2.6倍。