Gillette P C, Shannon C, Garson A, Porter C J, Ott D, Cooley D A, McNamara D G
J Am Coll Cardiol. 1983 May;1(5):1325-9. doi: 10.1016/s0735-1097(83)80147-8.
The sick sinus syndrome is being recognized with increasing frequency in children. Although it is sometimes benign, it can be serious or have fatal consequences. Fifty-one patients (mean age 10.5 years) underwent permanent cardiac pacing for sick sinus syndrome. Twenty patients had epicardial ventricular pacing and 12 had an epicardial atrial implant. Seven had endocardial atrial pacing, six epicardial atrioventricular (AV) sequential pacing, four epicardial universal pacing and two endocardial universal pacing. Of the 49 symptomatic patients, 45 had relief of symptoms. Eleven of 18 patients with associated tachyarrhythmias had amelioration of their tachycardia. There were no early but two late deaths unrelated to the pacemakers. Seven patients during a mean follow-up period of 26 months required reoperation for pacing lead or sensing problems. Permanent pacing for sick sinus syndrome in children is a safe and symptomatically effective procedure.
儿童病窦综合征的确诊率日益增高。尽管该病有时呈良性，但也可能很严重甚至导致致命后果。51例（平均年龄10.5岁）病窦综合征患儿接受了永久性心脏起搏治疗。20例行心外膜心室起搏，12例行心外膜心房植入。7例行心内膜心房起搏，6例行心外膜房室顺序起搏，4例行心外膜通用起搏，2例行心内膜通用起搏。49例有症状的患者中，45例症状缓解。18例合并快速性心律失常的患者中有11例心动过速得到改善。与起搏器无关的早期死亡病例为0，但有2例晚期死亡。平均随访26个月期间，7例患者因起搏导线或感知问题需要再次手术。儿童病窦综合征的永久性起搏是一种安全且症状改善有效的治疗方法。
