Sheppard J E, Dell P C
J Hand Surg Am. 1983 Mar;8(2):145-53. doi: 10.1016/s0363-5023(83)80005-7.
Although contrast media injected during arteriography is known to decrease microcirculatory blood flow and alter oxygen delivery capacity of the red blood cell, its effect on the vascular endothelium is unknown. This experiment was designed to determine if there were any alterations in arterial or venous endothelial anatomy by scanning electron microscopy and whether replant survival was decreased following arteriography. Our results suggest that when the injection pressure of arteriography is carefully controlled, the contrast media used in this experiment has no effect on vascular endothelium in rabbit ears examined 30 minutes and 24 hours after arteriography. Furthermore, the survival rate of replanted rabbit ears is not affected by arteriography 24 hours prior to replantation. We conclude that preoperative arteriography remains a valuable tool in the planning of free composite tissue transfer but, based on this study, cannot rule out mechanical complications of arteriography that may be deleterious to free tissue transfer.
尽管已知动脉造影期间注入的造影剂会减少微循环血流量并改变红细胞的氧输送能力，但其对血管内皮的影响尚不清楚。本实验旨在通过扫描电子显微镜确定动脉或静脉内皮解剖结构是否有任何改变，以及动脉造影后再植存活率是否降低。我们的结果表明，当动脉造影的注射压力得到仔细控制时，本实验中使用的造影剂在动脉造影后30分钟和24小时检查的兔耳中对血管内皮没有影响。此外，再植前24小时进行动脉造影不会影响兔耳再植的存活率。我们得出结论，术前动脉造影仍然是游离复合组织移植规划中的一个有价值的工具，但基于本研究，不能排除可能对游离组织移植有害的动脉造影机械并发症。
