Moffie D, Ongerboer de Visser B W, Stefanko S Z
J Neurol Sci. 1983 Feb;58(2):175-83. doi: 10.1016/0022-510x(83)90215-0.
Five cases of a tumour in the quadrigeminal area have been described, 4 of which could be verified by autopsy. In 2 cases with a metastasis in the tegmentum of the mesencephalon, a Parinaud syndrome was present. In 2 other cases, however, with extensive destruction of the quadrigeminal plate and of the posterior commissure this syndrome was not present. In the 5th case, with a big vascular tumour of the pineal area, disturbances of eye movements and pupils were also lacking. From these observations we may conclude that (1) destruction of the quadrigeminal plate has no influence upon vertical eye movements. (2) destruction of the posterior commissure, in combination with the quadrigeminal plate, is not always followed by disturbances of vertical eye movements. In man it is still not clear which structures are responsible for the performance of vertical eye movements.
已描述了5例四叠体区域肿瘤病例，其中4例可通过尸检证实。在2例中脑被盖有转移灶的病例中，出现了帕里诺德综合征。然而，在另外2例中，四叠体板和后连合广泛破坏的病例中，该综合征未出现。在第5例松果体区有大血管肿瘤的病例中，也未出现眼球运动和瞳孔异常。从这些观察结果我们可以得出结论：（1）四叠体板的破坏对垂直眼球运动没有影响。（2）后连合与四叠体板联合破坏并不总是伴有垂直眼球运动障碍。在人类中，仍不清楚哪些结构负责垂直眼球运动。
