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原发性肛管直肠恶性黑色素瘤

Primary anorectal malignant melanoma.

作者信息

Angerås U, Jönsson N, Jönsson P E

出版信息

J Surg Oncol. 1983 Apr;22(4):261-4. doi: 10.1002/jso.2930220411.

Abstract

Eleven patients with primary anorectal melanoma were analyzed retrospectively. Clinical symptoms and signs were rather unspecific; bleeding in nine, a palpable mass in five, and local pain in three patients. Two patients had the tumor diagnosed accidentally. In all patients the primary tumor was in an advanced stage. A summary of the histopathological characteristics is given in all patients. Six patients were subjected to abdominal perineal resection, four to local excision, and one to a colostomy followed by radiotherapy. All patients developed metastatic disease after a median time of 10 months. The median survival time was 14 months after both abdominal perineal resection and local excision. One patient is still alive after 11 years. Pertinent data form the literature are given.

摘要

对11例原发性肛管黑色素瘤患者进行了回顾性分析。临床症状和体征相当不具特异性;9例有出血,5例可触及肿块,3例有局部疼痛。2例患者肿瘤为偶然诊断。所有患者的原发性肿瘤均处于晚期。给出了所有患者组织病理学特征的总结。6例患者接受了腹会阴联合切除术,4例接受了局部切除术,1例接受了结肠造口术并随后进行放疗。所有患者中位10个月后均发生转移性疾病。腹会阴联合切除术和局部切除术后的中位生存时间均为14个月。1例患者在11年后仍然存活。给出了文献中的相关数据。

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