Spontaneous remission of severe hyperparathyroidism in chronic renal failure.

The sudden onset of hypocalcemia occurring in a patient undergoing hemodialysis led to the diagnosis of spontaneous remission of severe hyperparathyroidism. This was confirmed by a marked reduction in immunoreactive parathyroid hormone level. The hypocalcemia was controlled by 1,25-dihydroxycholecalciferol. A dramatic improvement of hyperparathyroid bone disease, as assessed by radiographic and histomorphometric examination, was observed.