Galle P C, Muss H B, McGrath K M, Stuart J J, Homesley H D
Obstet Gynecol. 1978 Jul;52(1 Suppl):9S-11S.
Two cases of thrombocytopenia, one resulting in bleeding, are reported in patients treated with prophylactic low-dose heparin. The evidence indicates that low-dose heparin was responsible. A review of the literature indicates that heparin-induced thrombocytopenia may be a common event. Since low-dose heparin has been shown to decrease the incidence of venous thrombosis and subsequent pulmonary embolism in patients undergoing major surgery, recommendations are made for monitoring platelet counts in such patients.
报告了两例接受预防性小剂量肝素治疗的患者出现血小板减少症的病例，其中一例导致出血。证据表明小剂量肝素是病因。文献综述表明肝素诱导的血小板减少症可能是常见事件。由于已证明小剂量肝素可降低接受大手术患者的静脉血栓形成及随后肺栓塞的发生率，因此建议对此类患者监测血小板计数。
