Shulman Y, Ware S, Al-Askari S, Morales P
Urology. 1983 Apr;21(4):379-81. doi: 10.1016/0090-4295(83)90156-5.
Fourteen patients with anaplastic seminoma were analyzed retrospectively. At the time of presentation anaplastic seminoma has similar prognosis stage for stage as the classic seminoma. However, the distinctive histologic findings and the high rates of local invasion and of elevations of serum beta-subunit human chorionic gonadotropin serve to distinguish anaplastic seminoma from the classic seminoma. These features, suggesting a possibly greater metastatic potential for anaplastic seminoma, warrant its continued identification as a distinct pathologic subtype.
对14例间变性精原细胞瘤患者进行了回顾性分析。初诊时，间变性精原细胞瘤与经典型精原细胞瘤在各分期的预后相似。然而，其独特的组织学表现、较高的局部侵犯率以及血清β亚单位人绒毛膜促性腺激素升高的情况，有助于将间变性精原细胞瘤与经典型精原细胞瘤区分开来。这些特征提示间变性精原细胞瘤可能具有更大的转移潜能，因此有必要继续将其认定为一种独特的病理亚型。
