Golubev L N
Vopr Onkol. 1983;29(3):36-9.
A method for constructing a mathematical model of pathological processes occurring in endometrial carcinoma is suggested. A multifactor analysis established that both combined therapy and complex radiation procedure involving the use of intracavitary insertion of 60Co spherical applicators may be equally effective in patients with stage I tumor identified by the factor model. A description of pathological conditions generally resulting in death of the patient within the first 2 years, irrespective of treatment modality, is given. The results of a study on pathologies involved in endometrial carcinoma on the basis of mathematical simulation refine the prognosis and allows to select adequate treatment.
提出了一种构建子宫内膜癌病理过程数学模型的方法。多因素分析表明,对于因子模型确定为I期肿瘤的患者,联合治疗以及采用60Co球形施源器腔内插入的综合放疗程序可能同样有效。文中给出了通常导致患者在头两年内死亡的病理状况描述,无论治疗方式如何。基于数学模拟对子宫内膜癌相关病理的研究结果完善了预后,并有助于选择合适的治疗方法。