Bödigheimer K, Ischinger T, Nowak F G, Delius W
Z Kardiol. 1983 Jan;72(1):48-52.
The hemodynamic effects of doxaminol, a new, orally applicable beta-agonist, chemically dissimilar to catecholamines, were studied in comparison to those of dobutamine by means of thermodilution. After single-dose application of doxaminol in cases of congestive heart failure, cardiac output and stroke volume increased, heart rate increased slightly, pulmonary and systemic arterial pressure remained constant, and peripheral vascular resistance decreased. No arrhythmias appeared, but one patient suffered an attack of angina.
通过热稀释法，研究了一种新型口服β-激动剂多沙米诺（化学结构与儿茶酚胺不同）与多巴酚丁胺相比的血流动力学效应。在充血性心力衰竭患者单剂量应用多沙米诺后，心输出量和每搏输出量增加，心率略有增加，肺和体循环动脉压保持不变，外周血管阻力降低。未出现心律失常，但有一名患者发生心绞痛发作。
