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终纹床核在大鼠被动防御行为形成中的作用

[Role of the stria terminalis in the formation of passive-defensive behavior in the rat].

作者信息

Loskutova L V, Vinnitskiĭ I M, Il'iuchenok R Iu

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1983 Jan-Feb;33(1):32-7.

PMID:6837157
Abstract

The formation of conditioned passive avoidance reaction (CAR) to a single pain reinforcement was studied in rats following electrolytic dissection of the stria terminalis (ST). Total ST dissection did not affect spontaneous motor activity and vegetative manifestations, though it deprived the animals of the ability to choose an adequate motor response when reproducing CAR. Hence, the ST integrity is essential for the formation of the motor component of the conditioned reaction. Separate dissection of the pre- and postcommissural ST components has shown that determining in the CAR formation is the integrity of the postcommissural component which contains fibres afferent for the amygdaloid complex. Dissection of the precommissural component consisting exclusively of efferent fibres did not affect CAR manifestation. The stria terminalis is probably an afferent activating way for the amygdaloid complex which achieves modulation of defensive conditioned behaviour.

摘要

在大鼠中,通过电解切断终纹床核(ST)后,研究了对单一疼痛强化刺激形成条件性被动回避反应(CAR)的情况。完全切断ST并不影响自发运动活动和植物性表现,尽管这使动物在再现CAR时丧失了选择适当运动反应的能力。因此,ST的完整性对于条件反应运动成分的形成至关重要。分别切断联合前和联合后ST成分表明,在CAR形成中起决定作用的是联合后成分的完整性,该成分包含杏仁复合体的传入纤维。仅由传出纤维组成的联合前成分的切断并不影响CAR的表现。终纹床核可能是杏仁复合体的一种传入激活途径,可实现对防御性条件行为的调节。

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