[Participation of subcortical formations in regulating motor asymmetry in the cat during elaboration of an instrumental active defensive reflex].

Parameters of motor asymmetry and the process of learning were studied in cats during elaboration of an active defensive reflex, following unilateral coagulation of various subcortical formations, predominantly of the extrapyramidal system. The changes of these parameters developed after the coagulation independently of each other. Lesion of the globus pallidus was attended, as a rule, with non-reversible changes of motor asymmetry and slight changes of the learning parameter. Destruction of the putamen and claustrum produced temporary disturbances of lateralization and learning processes. At early stages of the instrumental habit elaboration, the destruction of pathways passing in the internal capsule from different cortical structures to formations of the extrapyramidal system, brings about changes in the parameters of motor asymmetry and the learning process; at final stages--a similar lesion does not affect either parameter.