Gapochko K G, Misnikov O P, Kol'tsov B Iu, Shevchenko A I, Konovalov S I
Zh Mikrobiol Epidemiol Immunobiol. 1983 Feb(2):105-7.
The formulas indicating the relationship between the magnitude of aerosol aspiration doses of the vaccine preparation and the parameters of the dispersed composition of aerosol are presented. The results of calculation of the relationship between the proportion of the particles of the respirable fraction and the median mass diameter, as well as the root-mean-square deviation of the logarithms of the diameters, are given. To ensure the high effectiveness of immunization with the vaccine preparation, the use of aerosols with the median mass diameter between 1.0 mu and 3.5 mu is shown to be expedient.
给出了表明疫苗制剂气溶胶吸入剂量大小与气溶胶分散成分参数之间关系的公式。给出了可吸入部分颗粒比例与质量中值直径之间关系的计算结果，以及直径对数的均方根偏差。为确保疫苗制剂免疫的高效性，使用质量中值直径在1.0微米至3.5微米之间的气溶胶被证明是适宜的。
