Gloor H J, Nichols W K, Sorkin M I, Prowant B F, Kennedy J M, Baker B, Nolph K D
Am J Med. 1983 Apr;74(4):593-8. doi: 10.1016/0002-9343(83)91016-1.
Over a four-year period, 50 patients underwent continuous ambulatory peritoneal dialysis. After 24 months, 48 percent of the patients continued to receive continuous ambulatory peritoneal dialysis treatment (including those who underwent continuous ambulatory peritoneal dialysis with bottled solutions from 1977 to 1978). Using solutions in plastic bags, 63 percent of patients continued to undergo continuous ambulatory peritoneal dialysis after 24 months. The mortality rate at 24 months was 23 percent overall and 15 percent for those using plastic bags. There was an overall average of 2.4 episodes of peritonitis a year per patient and 1.3 episodes a year per patient from 1979 through 1980, when only the technique with plastic bags was used. The number of days a patient was hospitalized averaged 48 per year, and 37 days per year in 1979 and 1980. Fifty-five percent of catheters remained functional at 24 months. Other complications included 15 hernias, 15 skin and tunnel infections, 12 leaks, and five cuff extrusions. Improved catheters and further reductions in the incidence of peritonitis will most likely result in a decreased number of patients who withdraw from continuous ambulatory peritoneal dialysis therapy.
在四年时间里,50名患者接受了持续性非卧床腹膜透析。24个月后,48%的患者继续接受持续性非卧床腹膜透析治疗(包括那些在1977年至1978年使用瓶装溶液进行持续性非卧床腹膜透析的患者)。使用塑料袋装溶液的患者中,63%在24个月后继续接受持续性非卧床腹膜透析。24个月时的总体死亡率为23%,使用塑料袋装溶液的患者死亡率为15%。每名患者每年腹膜炎发作的总体平均次数为2.4次,在1979年至1980年期间(当时仅使用塑料袋装溶液的技术)每名患者每年为1.3次。患者每年平均住院天数为48天,在1979年和1980年为37天。55%的导管在24个月时仍能正常使用。其他并发症包括15例疝气、15例皮肤和隧道感染、12例渗漏以及5例袖套挤出。改进导管并进一步降低腹膜炎的发生率很可能会减少退出持续性非卧床腹膜透析治疗的患者数量。