硝酸钍和硝酸铀酰对小鼠睾丸的生精细胞计数及组织病理学影响。

Gametogenic count and histopathological effect of thorium nitrate and uranyl nitrate on mice testes.

作者信息

Jadon A, Mathur R

出版信息

Andrologia. 1983 Jan-Feb;15(1):40-3. doi: 10.1111/j.1439-0272.1983.tb00111.x.

DOI:10.1111/j.1439-0272.1983.tb00111.x

Abstract

Daily intraperitoneal administration of aqueous solution of 0.05 m mole/100 g b. wt. of uranyl nitrate and thorium nitrate has been observed for 7 days. Marked reduction in the seminiferous tubule diameter and gametogenic count was observed. Signs of testicular necrosis, exfoliation of germ cells, and karyolysis and karyorrhexis were seen in most of the tutubles. Mononucleate and polynucleate giant cells were also observed indicating prolonged pathological condition.

摘要

每天腹腔注射0.05毫摩尔/100克体重的硝酸铀酰和硝酸钍水溶液，持续观察7天。观察到生精小管直径和生精细胞数量显著减少。在大多数小管中可见睾丸坏死、生殖细胞脱落以及核溶解和核碎裂的迹象。还观察到单核和多核巨细胞，表明病理状况持续时间较长。