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人类膀胱壁内神经节。

Intramural ganglia of the human urinary bladder.

作者信息

Dixon J S, Gilpin S A, Gilpin C J, Gosling J A

出版信息

Br J Urol. 1983 Apr;55(2):195-8. doi: 10.1111/j.1464-410x.1983.tb06554.x.

DOI:10.1111/j.1464-410x.1983.tb06554.x
PMID:6839094
Abstract

The arrangement and distribution of intramural autonomic ganglion cells have been examined in samples of the dome and lateral walls of the human urinary bladder. Ganglia were frequently observed in samples removed from either site and possessed histochemical characteristics to support their classification as presumptive cholinergic neurons. Unlike pelvic autonomic neurons, intramural bladder ganglion cells are not associated with noradrenergic (possibly inhibitory) preganglionic nerve terminals. The widespread distribution of ganglion cells within the bladder wall serves to frustrate surgical attempts to denervate detrusor smooth muscle. The outcome of such operative procedures is likely to result in decentralisation rather than denervation of the urinary bladder.

摘要

对人膀胱穹窿和侧壁样本中的壁内自主神经节细胞的排列和分布进行了检查。在从这两个部位取出的样本中经常观察到神经节,且这些神经节具有组织化学特征,以支持将它们分类为推定的胆碱能神经元。与盆腔自主神经元不同,壁内膀胱神经节细胞与去甲肾上腺素能(可能是抑制性的)节前神经末梢无关。神经节细胞在膀胱壁内的广泛分布使得对逼尿肌平滑肌进行去神经支配的手术尝试受挫。此类手术操作的结果可能导致膀胱的去中枢化而非去神经支配。

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