子宫内暴露于己烯雌酚对男孩青春期启动年龄及青春期后激素水平的影响。
Effect of in-utero exposure to diethylstilbestrol on age at onset of puberty and on postpubertal hormone levels in boys.
作者信息
Ross R K, Garbeff P, Paganini-Hill A, Henderson B E
出版信息
Can Med Assoc J. 1983 May 15;128(10):1197-8.
Abstract
A group of boys exposed to diethylstilbestrol (DES) in utero who had earlier been found to have urogenital abnormalities were studied for evidence of later effects of DES on their health, physical development and hormonal status. They showed no difference in age at onset of puberty, development of sexual characteristics or hormone levels from boys of the same age who had not been exposed to DES. However, the exposed group tended to have smaller testes.
摘要
一组在子宫内接触过己烯雌酚（DES）的男孩，早期被发现有泌尿生殖系统异常，对他们进行研究以寻找DES对其健康、身体发育和激素状况后期影响的证据。他们在青春期开始的年龄、性特征发育或激素水平方面与未接触DES的同龄男孩没有差异。然而，接触组的睾丸往往较小。
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本文引用的文献
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Effects of prenatal maternal estrogen on the male urogenital system.产前母体雌激素对男性泌尿生殖系统的影响。
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Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol.子宫内暴露于己烯雌酚的女性的生育能力及妊娠结局
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Follow-up study of male and female offspring of DES-exposed mothers.己烯雌酚暴露母亲的男性和女性后代的随访研究。
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