Storme G A, Mareel M M, Dragonetti C H
Cell Biol Int Rep. 1983 Feb;7(2):99-107. doi: 10.1016/0309-1651(83)90022-x.
Spheroids of MO4 mouse fibrosarcoma cells were irradiated with single doses of photons between 1 and 50 Gy. Growth of irradiated spheroids was followed in suspension culture and after explantation on glass. We found that MO4 spheroids recovered from higher doses of irradiation when they were explanted on glass than when they were kept in suspension culture. These results suggest that irradiated MO4 cell populations may become anchorage-dependent for growth.
用1至50戈瑞的单剂量光子对MO4小鼠纤维肉瘤细胞球体进行照射。在悬浮培养以及接种到玻璃片上之后，对受照射球体的生长情况进行跟踪。我们发现，当MO4球体接种到玻璃片上时，相较于悬浮培养，它们从更高剂量照射中恢复的能力更强。这些结果表明，受照射的MO4细胞群体在生长方面可能会变得依赖贴壁。
