Mikami K, Ng S F
Exp Cell Res. 1983 Mar;144(1):25-30. doi: 10.1016/0014-4827(83)90437-8.
The micronucleus of Paramecium tetraurelia normally gives rise to the macronucleus by going through the series of nuclear events of meiosis, mitosis and fusion during sexual reproduction. By transplanting the micronucleus from vegetative cells into early exconjugants, we have persuaded the micronucleus to take a short cut to differentiate directly into a macronucleus. This demonstrates that the course of development of the micronucleus is flexible and can be altered by stage-specific cytoplasmic factors.
四膜虫的小核通常在有性生殖过程中通过减数分裂、有丝分裂和融合等一系列核事件产生大核。通过将营养细胞中的小核移植到早期接合后体中，我们促使小核走捷径直接分化为大核。这表明小核的发育过程具有灵活性，并且可以被阶段特异性的细胞质因子改变。
