Pashley N R
Int J Pediatr Otorhinolaryngol. 1983 Jan;5(1):59-65. doi: 10.1016/s0165-5876(83)80008-1.
Acquired incomplete subglottic stenosis in children has historically been managed by serial bouginage of the strictured region sometimes accompanied by injection or systemic administration of corticosteroid medications. The forceful stretching of the scar whilst awaiting growth of the region to compensate for scar contracture, however, dooms that child to a prolonged period of waiting for an unpredictable result with a tracheotomy in place. Recently, laryngo-tracheoplasty has been undertaken in younger age groups and in a review of 30 children, with very similar types of stenosis, it was noted that the 19 children managed only by bouginage (with or without steroids) (1) had a much less predictable result, (2) were only able to be ultimately decannulated 52.6% of the time, and (3) had a mean time from the initiation of treatment to decannulation of 620.1 days. This contrasted very sharply with 11 children who underwent an elective laryngo-tracheoplasty of whom 81.8% were able to be decannulated with a mean time from the initiation of treatment of 82.33 days. It was noteworthy that of those managed by dilation alone 9 children (47.4%) were tracheotomy-dependent following treatment and 7 of these were aphonic (36.8% of the total group), whereas in the surgically managed group, 2 were tracheotomy-dependent (18.2% of the total), and all could talk around their tracheotomy tube. The methods and mechanics of such therapeutic approaches are examined and discussed.
儿童后天性声门下狭窄在历史上一直通过对狭窄区域进行系列探条扩张来处理,有时还会辅以皮质类固醇药物注射或全身给药。然而,在等待该区域生长以补偿瘢痕挛缩的同时对瘢痕进行强力拉伸,会使患儿注定要长时间等待一个不可预测的结果,且在此期间需进行气管切开。最近,喉气管成形术已应用于较年轻的年龄组,在一项对30名患有非常相似类型狭窄的儿童的回顾中发现,仅接受探条扩张(无论是否使用类固醇)治疗的19名儿童,(1)结果的可预测性要低得多,(2)最终能够拔管的比例仅为52.6%,(3)从开始治疗到拔管的平均时间为620.1天。这与11名接受择期喉气管成形术的儿童形成了鲜明对比,这些儿童中有81.8%能够拔管,从开始治疗到拔管的平均时间为82.33天。值得注意的是,在仅接受扩张治疗的儿童中,有9名(47.4%)在治疗后仍依赖气管切开,其中7名失音(占总人数的36.8%),而在手术治疗组中,有2名依赖气管切开(占总人数的18.2%),且所有人都能在气管切开套管周围发声。本文对这些治疗方法的方式和机制进行了研究和讨论。