Wittrin G, Clemens M, Arndt M, Rühland D
Res Exp Med (Berl). 1978 Jul 24;173(1):95-103. doi: 10.1007/BF01851377.
3 cm of the common bile duct was removed in 19 dogs and the defect was bridged by an autologous vein. The interposition of a vein graft was performed with a double end-to-end anastomosis. In four cases a T-drain was additionally placed into the transplant. GOT, GPT, LDH, AP and bilirubin were tested in regular intervals. The patency of the transplant was proved by radiography with dogs which survived longer than 6 weeks. 5 dogs died within the first 4 weeks, 4 were killed after 2 months, because of incrustation of the T-drain for a regular percutaneous rinsing of the drainage was not possible. 10 dogs survived for 6 to 12 months. These animals showed increasing laboratory results up to two months, then the tests normalized. The function of the transplanted vein was without complication and the liver histology did not show any pathological alteration. After two months the transplanted vein was bridged by bile duct epithelium.
在19只犬中切除3厘米胆总管，缺损处用自体静脉搭桥。采用双端端吻合进行静脉移植。4例中另外在移植处放置了T形引流管。定期检测谷草转氨酶（GOT）、谷丙转氨酶（GPT）、乳酸脱氢酶（LDH）、碱性磷酸酶（AP）和胆红素。通过对存活超过6周的犬进行造影检查证明移植通畅。5只犬在最初4周内死亡，4只在2个月后因T形引流管结痂无法进行常规经皮冲洗引流而被处死。10只犬存活6至12个月。这些动物在两个月内实验室检查结果不断升高，之后各项检测指标恢复正常。移植静脉功能无并发症，肝脏组织学未显示任何病理改变。两个月后，移植静脉被胆管上皮覆盖。
