Jostarndt L, Thermann M, Jerusalem C R, Zelder O
Res Exp Med (Berl). 1978 Aug 15;173(2):187-91. doi: 10.1007/BF01851876.
Thioacetamide-fed rats developed cirrhosis with portal hypertension (P portal=23.0 +/- 5.2 cm H2O, controls: 14.4 +/- 1.0 cm H2O). The PO2 of liver tissue was markedly reduced in cirrhosis (PO2=7.6 +/- 3.4 torr, controls 22.3 +/- 5.8 torr), and the aortal pH was significantly lower as well. No correlation was found between portal hypertension, development of large--nodular cirrhosis, and ascites.
用硫代乙酰胺喂养的大鼠出现了伴有门静脉高压的肝硬化（门静脉压力=23.0±5.2 cmH₂O，对照组：14.4±1.0 cmH₂O）。肝硬化时肝组织的氧分压显著降低（氧分压=7.6±3.4托，对照组为22.3±5.8托），主动脉pH值也明显较低。未发现门静脉高压、大结节性肝硬化的发展与腹水之间存在相关性。
