Koyama T, Shimosaka S, Uchibori M, Aii H
No Shinkei Geka. 1983 Feb;11(2):195-201.
Three adult patients with a clinical diagnosis of Chiari malformation were examined by computed tomography after intrathecal injection of metrizamide via the lumbar route. In all patients Chiari malformation was demonstrated as a soft tissue oval mass at the level of C1-C2 vertebral body that was intradural and posterior to the medulla and the upper cervical spinal cord. These findings were more accurately visualized in saggital and in frontal reconstructed CTs. In one patient the spinal cord was measurably enlarged at the upper thoracic level. A delayed scan was obtained in another case at 24 hours after the injection and the syrinx was remained opacified whereas the density of cerebrospinal fluid and parenchyma decreased. In the third patient no abnormality of the cord was demonstrated either in CT or myelography. High resolution CT, especially reconstruction-CT appears to be more reliable than myelography and should be the examination of choice in the diagnosis of Chiari malformation.
三名临床诊断为Chiari畸形的成年患者经腰椎途径鞘内注射甲泛葡胺后接受了计算机断层扫描检查。在所有患者中,Chiari畸形均表现为C1 - C2椎体水平的椭圆形软组织肿块,位于硬脊膜内,延髓和上颈髓后方。这些发现于矢状面和冠状面重建CT图像上显示得更为清晰。在一名患者中,上胸段脊髓明显增粗。另一名患者在注射后24小时进行了延迟扫描,脊髓空洞仍显影,而脑脊液和脑实质密度降低。在第三名患者中,CT或脊髓造影均未显示脊髓异常。高分辨率CT,尤其是重建CT似乎比脊髓造影更可靠,应作为Chiari畸形诊断的首选检查方法。