Lijinsky W, Reuber M D
Toxicol Appl Pharmacol. 1983 Mar 30;68(1):43-53. doi: 10.1016/0041-008x(83)90353-8.
A chronic toxicity test was carried out in groups of 20 male and female F344 rats with vinyl acetate dissolved in drinking water at two concentrations, 2500 and 1000 mg/liter. Treatment lasted for 2 years and did not lead to early death of the animals compared with untreated controls. The incidence of most types of neoplasm was similar in the treated and control groups. However, six females receiving the higher dose of vinyl acetate had adenoma or carcinoma of the thyroid and five had carcinoma of the uterus; the latter were not seen in the controls.
对20只雄性和雌性F344大鼠进行了慢性毒性试验，将醋酸乙烯酯以2500毫克/升和1000毫克/升两种浓度溶解于饮用水中。与未处理的对照组相比，处理持续2年，未导致动物过早死亡。处理组和对照组中大多数肿瘤类型的发生率相似。然而，接受较高剂量醋酸乙烯酯的6只雌性大鼠患有甲状腺腺瘤或癌，5只患有子宫癌；对照组中未见后者。
