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[组织形态计量学对W. 拜尔衰老函数指数的贡献]

[Histomorphometric contribution to W. Beier's exponent of the aging function].

作者信息

Rother P, Jahn W, Blume R, Walther M

出版信息

Z Alternsforsch. 1983 Jan-Feb;38(1):3-9.

PMID:6845746
Abstract

We determined aging changes of the nucleus-cytoplasm-relation in the epithelium of the epiglottis and intestine of human beings and rats. The results were compared with data about the proliferation of connective tissue and the decrease of muscle cells in the wall of the intestine and in the ciliary muscle. We adapted exponential functions to the measured results. For comparing the several equations and the derivable aging velocities, the nucleus-cytoplasm-relation must be transformed into nucleus volume rate of the total cell volume. Similarities in the decrease of the aging speed in the course of life and in the value of the exponent of the aging function by W. Beier (approximately equal to 0,03) were demonstrated.

摘要

我们测定了人类和大鼠会厌及肠道上皮细胞中核质关系的衰老变化。将结果与关于肠道壁和睫状肌中结缔组织增殖及肌肉细胞减少的数据进行了比较。我们用指数函数拟合测量结果。为了比较几个方程以及可推导的衰老速度,必须将核质关系转化为细胞核体积占总细胞体积的比例。结果表明,在生命过程中衰老速度的降低以及W. 拜尔衰老函数指数值(约等于0.03)存在相似性。

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