Marti H R
Z Gesamte Inn Med. 1983 Feb 1;38(3):65-6.
The simplest methods for the diagnosis of thalassaemias are the morphology of erythrocytes, the Hb-F-elution test and the Hb H Heinz bodies test. In order to prove the sickle cell anomaly sickle cell preparation and Hb-S-precipitation test can be performed in every laboratory. By means of the isopropanol precipitation test or the Heinz bodies test can be searched for instable haemoglobins without any laboratory expenditure. On the other hand, haemoglobins with increased oxygen affinity demand a measurement of the oxygen affinity of the erythrocytes. However, simple fluorescence or dye-stuff methods are out our disposal for the most important erythrocytic enzymopenias.
地中海贫血最简单的诊断方法是红细胞形态学检查、Hb - F洗脱试验和Hb H Heinz小体试验。为了证实镰状细胞异常，每个实验室都可以进行镰状细胞制备和Hb - S沉淀试验。通过异丙醇沉淀试验或Heinz小体试验，可以在无需任何实验室费用的情况下检测不稳定血红蛋白。另一方面，对氧亲和力增加的血红蛋白需要测量红细胞的氧亲和力。然而，对于最重要的红细胞酶缺乏症，我们没有简单的荧光或染料方法可用。
