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[恶性黑色素瘤患者、内源性湿疹患者及健康人群的标准化回忆抗原检测]

[Standardized recall antigen testing in patients with malignant melanoma, endogenous eczema patients and healthy humans].

作者信息

Stenger D, Delbrück H, Krumrey K, Zaun H

出版信息

Z Hautkr. 1983 Mar 1;58(5):293-304.

PMID:6845797
Abstract

By means of a new test kit (Multitest), intracutaneous tests have been performed on several groups of patients in order to evaluate the degree of cellular immunity. This test system affords the simultaneous application of seven quantitatively and qualitatively standardized antigens. In comparison to healthy people, patients suffering from malignant melanoma showed a slightly higher immunity reaction whereas patients with atopic dermatitis revealed a significantly lesser degree of reactivity to the recall-antigens. Chemotherapy with Dacarbazine did not change the amount of reactivity to the Multitest. This paper discusses the advantages of the new test kit as well as the difficulties of recall-antigen testing with regard to the evaluation of cellular immunity.

摘要

通过一种新的检测试剂盒(多重检测试剂盒),对几组患者进行了皮内试验,以评估细胞免疫程度。该检测系统可同时应用七种定量和定性标准化抗原。与健康人相比,患有恶性黑色素瘤的患者免疫反应略高,而特应性皮炎患者对回忆抗原的反应程度明显较低。用达卡巴嗪进行化疗并未改变对多重检测试剂盒的反应量。本文讨论了这种新检测试剂盒的优点以及在评估细胞免疫方面进行回忆抗原检测的困难。

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