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与广泛血管手术相关的血容量和血流动力学变化

Blood volume and hemodynamic changes in relation to extensive vascular operations.

作者信息

Sørensen M B, Engell H C

出版信息

Surg Gynecol Obstet. 1978 Sep;147(3):369-75.

PMID:684588
Abstract

In 37 patients without cardiopulmonary insufficiency, postoperative changes in blood volume have been correlated to changes in the systemic and the central circulation. Postoperatively, the blood volume had decreased an average of 8 per cent, and diastolic blood pressure, 7 per cent, while cardiac index had increased 14 per cent and heart rate, 16 per cent. No significant changes could be demonstrated in pulmonary artery pressures, central venous pressure or invascular resistance. A highly significant correlation between the blood volume and pulmonary artery pressures and a significant correlation between the blood volume and central venous pressure were noted. Hematocrit was negatively correlated to vascular resistance. It is concluded that an unchanged blood volume during the first postoperative hours results in increased pulmonary artery pressures and central venous pressure. Therefore, in patients suspected of having increased pulmonary artery pressures, complete restoration of blood volume should take place over some hours postoperatively. An increase in hematocrit over normal values should be avoided.

摘要

在37例无心肺功能不全的患者中,术后血容量的变化与体循环和中心循环的变化相关。术后,血容量平均减少了8%,舒张压降低了7%,而心脏指数增加了14%,心率增加了16%。肺动脉压、中心静脉压或血管阻力无明显变化。血容量与肺动脉压之间存在高度显著的相关性,血容量与中心静脉压之间存在显著相关性。血细胞比容与血管阻力呈负相关。得出的结论是,术后最初几个小时血容量不变会导致肺动脉压和中心静脉压升高。因此,对于怀疑肺动脉压升高的患者,术后应在数小时内完全恢复血容量。应避免血细胞比容超过正常值。

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