Briese V, Hofmann R, Meissner J, Straube W
Zentralbl Gynakol. 1983;105(4):229-35.
Secretory immunoglobulin A (S-IgA) is an essential part of local immune system of female genital tract. Accordingly the estimation of S-IgA in female genital secretions is important for judgement of immunologic problems in female genital tract. The estimation of S-IgA was carried out by means of an antiserum against human secretory component (anti SC) and S-IgA standard. It was used the single radial immunodiffusion according to Mancini and co-workers. Our results refer to changes in the quantity of S-IgA locally produced in the mucous membranes of female genital tract correlated to the menstrual cycle. The essential results are a decrease of S-IgA in midcycle in cervical mucus and vaginal fluids as well as of fertile and sterile patients.
分泌型免疫球蛋白A（S-IgA）是女性生殖道局部免疫系统的重要组成部分。因此，评估女性生殖道分泌物中的S-IgA对于判断女性生殖道的免疫问题很重要。S-IgA的评估是通过抗人分泌成分抗血清（抗SC）和S-IgA标准品进行的。采用了曼奇尼及其同事的单向放射免疫扩散法。我们的结果涉及女性生殖道黏膜局部产生的S-IgA数量的变化，这些变化与月经周期相关。主要结果是，在月经周期中期，宫颈黏液和阴道分泌物中S-IgA减少，无论是可育还是不育患者均如此。
