Hurlow R A, Chandler S T, Hardman J, Strachan C J
Surgery. 1978 Aug;84(2):278-82.
In 41 patients with severe claudication, the time taken for an intravenously injected isotope bolus of TC99m pertechnetate to pass from the aortic bifurcation to the common femoral arteries was measured using a gamma camera and computer. This isotope transit time (ITT) then was correlated with the severity of aortoiliac disease determined arteriographically. Highly significant differences in ITT were found between normal vessels and those with minor stenosis of less than 50%, major stenosis of 50% or more, or complete occlusion. With major disease there was a longer ITT than with minor disease (P less than 0.01). ITT gave a greater degree of differentiation between disease groups than did thigh/brachial pressure index, as measured by Doppler ultrasound in the same patients, and was not influenced by superficial femoral artery occlusion.
在41例严重跛行患者中，使用γ相机和计算机测量静脉注射高锝酸盐99m锝同位素团注从主动脉分叉处至股总动脉的通过时间。然后将该同位素通过时间（ITT）与经动脉造影确定的主髂动脉疾病严重程度相关联。发现正常血管与狭窄小于50%的轻度狭窄、50%或以上的重度狭窄或完全闭塞的血管之间的ITT存在高度显著差异。患有严重疾病的患者ITT比患有轻度疾病的患者更长（P<0.01）。与通过对同一患者进行多普勒超声测量的大腿/肱动脉压力指数相比，ITT在疾病组之间的区分度更高，并且不受股浅动脉闭塞的影响。
